Our division is active in both basic and clinical research. The basic science laboratory is involved in the study of diabetic and hypertensive renal disease, as well as developmental biology of the embryo and kidney. In addition, the division faculty are engaged in focused study of:

  • Glucose transporter roles in various disease states, particularly diabetic nephropathy, nondiabetic glomerulosclerosis, the GLUT1 Deficiency Syndrome, embryonic development with and without maternal diabetes, and hypoxic stress. The facilitative glucose transporters, or GLUTs, play key roles in embryonic and renal development under normal and pathologic conditions. They are also involved in the development of diabetic and nondiabetic glomerulosclerosis which has important implications for chronic renal disease.
  • Potential roles of recently discovered sodium-hydrogen antiporters in hypertension, and in renal disease with and without diabetes.
  • Role of CTGF in diabetic nephropathy.

The clinical research studies address novel questions relevant to modeling of the course of anemia in end stage renal disease patients and studies assessing the efficiencies of different dialysis prescriptions.

For more details about individual faculty research interests, please view their bios on the faculty page.

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