Scott L. Silliman M.D. Professor & Medical Director, Comprehensive Stroke Program; Program Director, Vascular Neurology Fellowship Department: Department of Neurology Business Phone: (904) 244-9896 Business Email: scott.silliman@jax.ufl.edu Appointments and Locations Board Certifications NeurologyVascular Neurology Show More Clinical Profile Specialties Multiple SclerosisNeurologyVascular Neurology Interests Clinical Special Interests: Cerebrovascular disease; multiple sclerosisResearch Special Interests: Stroke therapeutics, swallowing dysfunction associated with stroke, and stroke genetics Show More Publications 2023Symptomatic idiopathic intracranial hypertension triggered by Ramadan intermittent fasting: a case report.Nutritional neuroscience.():1-4[DOI] 10.1080/1028415X.2023.2272090.[PMID] 37948151.PubMed·Publisher's Site2021Rare Missense Functional Variants at COL4A1 and COL4A2 in Sporadic Intracerebral Hemorrhage.Neurology.97(3):e236-e247[DOI] 10.1212/WNL.0000000000012227.[PMID] 34031201.5 citations·PubMed·Publisher's Site2020Exercise-based swallowing intervention (McNeill Dysphagia Therapy) with adjunctive NMES to treat dysphagia post-stroke: A double-blind placebo-controlled trial.Journal of oral rehabilitation.47(4):501-510[DOI] 10.1111/joor.12928.[PMID] 31880338.35 citations·PubMed·Publisher's Site2019Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis.JAMA neurology.76(4):480-491[DOI] 10.1001/jamaneurol.2018.4519.[PMID] 30726504.36 citations·PubMed·Publisher's Site2019Genome-wide association study of cerebral small vessel disease reveals established and novel loci.Brain : a journal of neurology.142(10):3176-3189[DOI] 10.1093/brain/awz233.[PMID] 31430377.63 citations·PubMed·Publisher's Site201817p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage.Stroke.49(7):1618-1625[DOI] 10.1161/STROKEAHA.117.020091.[PMID] 29915124.20 citations·PubMed·Publisher's Site2018Analysis of shared heritability in common disorders of the brain.Science (New York, N.Y.).360(6395):-[DOI] 10.1126/science.aap8757.[PMID] 29930110.1137 citations·PubMed·Publisher's Site2018Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypesNeurology-Genetics.4(6):e293-[DOI] 10.1212/NXG.0000000000000293.[PMID] .PubMed·Publisher's Site2018Diagnosis and Management of Acute Ischemic Stroke.Mayo Clinic proceedings.93(4):523-538[DOI] 10.1016/j.mayocp.2018.02.013.[PMID] 29622098.52 citations·PubMed·Publisher's Site2017Multiplanar computed tomography reconstruction to aid in recognition of the middle cerebral artery "Dot" sign: The sagittal string sign.SAGE open medical case reports.5():2050313X17748864-[DOI] 10.1177/2050313X17748864.[PMID] 29318017.2 citations·PubMed·Publisher's Site2016Bacterial Endocarditis and Cerebrovascular Disease.Current neurology and neuroscience reports.16(12):104-[DOI] .[PMID] 27815693.11 citations·PubMed·Publisher's Site2016Clinical Variables Associated with Hydration Status in Acute Ischemic Stroke Patients with Dysphagia.Dysphagia.31(1):60-5[DOI] 10.1007/s00455-015-9658-6.[PMID] 26497649.25 citations·PubMed·Publisher's Site2016Genetic variants in CETP increase risk of intracerebral hemorrhage.Annals of neurology.80(5):730-740[DOI] 10.1002/ana.24780.[PMID] 27717122.26 citations·PubMed·Publisher's Site2015Common Variation in Col4A1/Col4A2 Is Associated With Sporadic Cerebral Small Vessel DiseaseNeurology.84(9):918-926[DOI] 10.1212/WNL.0000000000001309.[PMID] 25653287.89 citations·PubMed·Publisher's Site2015Rare Coding Variation and Risk of Intracerebral Hemorrhage.Stroke.46(8):2299-301[DOI] 10.1161/STROKEAHA.115.009838.[PMID] 26111891.7 citations·PubMed·Publisher's Site2014APOE ε variants increase risk of warfarin-related intracerebral hemorrhage.Neurology.83(13):1139-46[DOI] 10.1212/WNL.0000000000000816.[PMID] 25150286.25 citations·PubMed·Publisher's Site2014Assessing the impact of health literacy on education retention of stroke patients.Preventing chronic disease.11():E55-[DOI] 10.5888/pcd11.130259.[PMID] 24721215.19 citations·PubMed·Publisher's Site2014Clinical Factors Impacting Dehydration in Acute StrokeInternational Journal of Stroke.9(3, SI):76-77[DOI] .[PMID] .PubMed·Publisher's Site2014Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage.American journal of human genetics.94(4):511-21[DOI] 10.1016/j.ajhg.2014.02.012.[PMID] 24656865.193 citations·PubMed·Publisher's Site2013Burden of blood pressure-related alleles is associated with larger hematoma volume and worse outcome in intracerebral hemorrhage.Stroke.44(2):321-6[DOI] 10.1161/STROKEAHA.112.675181.[PMID] 23321443.27 citations·PubMed·Publisher's Site2013Characteristics and outcomes of cocaine-related spontaneous intracerebral hemorrhages.ISRN neurology.2013():124390-[DOI] 10.1155/2013/124390.[PMID] 23533805.4 citations·PubMed·Publisher's Site2013Common variants within oxidative phosphorylation genes influence risk of ischemic stroke and intracerebral hemorrhage.Stroke.44(3):612-9[DOI] 10.1161/STROKEAHA.112.672089.[PMID] 23362085.28 citations·PubMed·Publisher's Site2013Dysphagia, nutrition, and hydration in ischemic stroke patients at admission and discharge from acute care.Dysphagia.28(1):69-76[DOI] 10.1007/s00455-012-9414-0.[PMID] 22684924.93 citations·PubMed·Publisher's Site2013Heritability estimates identify a substantial genetic contribution to risk and outcome of intracerebral hemorrhage.Stroke.44(6):1578-83[DOI] 10.1161/STROKEAHA.111.000089.[PMID] 23559261.69 citations·PubMed·Publisher's Site2013Novel insights into the genetics of intracerebral hemorrhage.Stroke.44(6 Suppl 1):S137-[DOI] 10.1161/STROKEAHA.113.001912.[PMID] 23709713.5 citations·PubMed·Publisher's Site2012Burden of risk alleles for hypertension increases risk of intracerebral hemorrhage.Stroke.43(11):2877-83[DOI] 10.1161/STROKEAHA.112.659755.[PMID] 22933587.33 citations·PubMed·Publisher's Site2012Cogan syndrome: an analysis of reported neurological manifestations.The neurologist.18(2):55-63[DOI] 10.1097/NRL.0b013e31823fa3a0.[PMID] 22367829.11 citations·PubMed·Publisher's Site2012Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.Neurology.78(5):334-41[DOI] 10.1212/WNL.0b013e3182452b40.[PMID] 22262751.74 citations·PubMed·Publisher's Site2011APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study.The Lancet. Neurology.10(8):702-9[DOI] 10.1016/S1474-4422(11)70148-X.[PMID] 21741316.127 citations·PubMed·Publisher's Site2011Apoe Genotype Predicts Hematoma Volume and Expansion in Intracerebral Hemorrhage.42():E102-[DOI] .[PMID] .PubMed·Publisher's Site2011Boosting enrolment in clinical trials: validation of a regional network model.Clinical trials (London, England).8(5):645-53[DOI] 10.1177/1740774511414925.[PMID] 21824978.4 citations·PubMed·Publisher's Site2011Genome Wide Association Study of Intracerebral Hemorrhage.42():E218-E219[DOI] .[PMID] .PubMed·Publisher's Site2011Local Hospital Networks for Clinical Trials in Stroke.42():E158-E159[DOI] .[PMID] .PubMed·Publisher's Site2011Variants At Apoe Influence Risk of Deep and Lobar Intracerebral Hemorrhage.42():E185-[DOI] .[PMID] .PubMed·Publisher's Site2010Analysis of a physician tool for evaluating dysphagia on an inpatient stroke unit: the modified Mann Assessment of Swallowing Ability.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.19(1):49-57[DOI] 10.1016/j.jstrokecerebrovasdis.2009.03.007.[PMID] 20123227.73 citations·PubMed·Publisher's Site2010Phenotypic Characteristics By Consent Status: Comparison of Self-Consent, Proxy-Consent, and Waiver of Consent in the Genetics of Cerebral Hemorrhage in Anticoagulation (Gocha) Study.41():E337-E338[DOI] .[PMID] .PubMed·Publisher's Site2010Variants at APOE influence risk of deep and lobar intracerebral hemorrhage.Annals of neurology.68(6):934-43[DOI] 10.1002/ana.22134.[PMID] 21061402.200 citations·PubMed·Publisher's Site2009CADASIL disease, an inherited slowly progressive vascular dementia: case report with radiologic and electron microscopic findings.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.18(6):491-3[DOI] 10.1016/j.jstrokecerebrovasdis.2009.02.004.[PMID] 19900654.2 citations·PubMed·Publisher's Site2009Exploiting common genetic variation to make anticoagulation safer.Stroke.40(3 Suppl):S64-6[DOI] 10.1161/STROKEAHA.108.533190.[PMID] 19150865.19 citations·PubMed·Publisher's Site2008A systematic review of outcomes in patients with staged carotid artery stenting and coronary artery bypass graft surgery.Stroke.39(2):361-5[DOI] 10.1161/STROKEAHA.107.495010.[PMID] 18174484.41 citations·PubMed·Publisher's Site2008Hypertriglyceridemia and ischemic stroke.European neurology.60(6):269-78[DOI] 10.1159/000157880.[PMID] 18824854.35 citations·PubMed·Publisher's Site2008Impact of restricting enrollment in stroke genetics research to adults able to provide informed consent.Stroke.39(3):831-7[DOI] 10.1161/STROKEAHA.107.494518.[PMID] 18258838.9 citations·PubMed·Publisher's Site2008Long-Term Behavioral Symptoms in Ischemic Stroke Survivors.39():619-[DOI] .[PMID] .PubMed·Publisher's Site2008Long-Term Cognitive Function in Survivors of First-Ever Ischemic Stroke.39():707-[DOI] .[PMID] .PubMed·Publisher's Site2008Proband race/ethnicity affects pedigree completion rate in a genetic study of ischemic stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.17(5):299-302[DOI] 10.1016/j.jstrokecerebrovasdis.2008.02.011.[PMID] 18755410.PubMed·Publisher's Site2008Screening of Long-Term Functional Outcomes in Survivors of First-Ever Ischemic Stroke.39():696-[DOI] .[PMID] .PubMed·Publisher's Site2008Structural genomic variation in ischemic stroke.Neurogenetics.9(2):101-8[DOI] 10.1007/s10048-008-0119-3.[PMID] 18288507.25 citations·PubMed·Publisher's Site2007A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release.The Lancet. Neurology.6(5):414-20[DOI] .[PMID] 17434096.145 citations·PubMed·Publisher's Site2007Sex differences in stroke evaluations in the Ischemic Stroke Genetics Study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.16(5):187-93[DOI] .[PMID] 17845914.3 citations·PubMed·Publisher's Site2007Sex differences in stroke severity, symptoms, and deficits after first-ever ischemic stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.16(1):34-9[DOI] .[PMID] 17689390.48 citations·PubMed·Publisher's Site2006Dysphagia and nutritional status at the time of hospital admission for ischemic stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.15(4):164-71[DOI] .[PMID] 17904070.39 citations·PubMed·Publisher's Site2006Family history of stroke and severity of neurologic deficit after stroke.Neurology.67(8):1396-402[DOI] .[PMID] 17060565.17 citations·PubMed·Publisher's Site2006Interobserver agreement in the trial of org 10172 in acute stroke treatment classification of stroke based on retrospective medical record review.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.15(6):266-72[DOI] .[PMID] 17904086.41 citations·PubMed·Publisher's Site2003Simultaneous bilateral hypertensive putaminal hemorrhages.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.12(1):44-6[DOI] .[PMID] 17903903.5 citations·PubMed·Publisher's Site2003Spouses and unrelated friends of probands as controls for stroke genetics studies.Neuroepidemiology.22(4):239-44[DOI] .[PMID] 12792144.5 citations·PubMed·Publisher's Site2003The Ischemic Stroke Genetics Study (ISGS) Protocol.BMC neurology.3():4-[DOI] .[PMID] 12848902.39 citations·PubMed·Publisher's Site2003Use of a field-to-stroke center helicopter transport program to extend thrombolytic therapy to rural residents.Stroke.34(3):729-33[DOI] .[PMID] 12624299.99 citations·PubMed·Publisher's Site2002Mendelian and mitochondrial disorders associated with stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.11(5):252-64[DOI] .[PMID] 17903883.4 citations·PubMed·Publisher's Site2001Images in clinical medicine. Hemorrhagic transformation of a cerebral infarct.The New England journal of medicine.345(15):1105-[DOI] .[PMID] 11596590.PubMed·Publisher's Site1999Vascular risk factors in cocaine users with stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.8(4):254-8[DOI] .[PMID] 17895173.3 citations·PubMed·Publisher's Site1995The Warfarin-Aspirin Symptomatic Intracranial Disease Study.Neurology.45(8):1488-93[DOI] .[PMID] 7644046.416 citations·PubMed·Publisher's Site Show More Office Information Academic Office 9th Floor, Tower I580 West 8th Street, T17Jacksonville, FL 32209(904) 244-9831 scott.silliman@jax.ufl.edu Administrative Manager Sarah Conway(904) 244-9896SarahE.conway@jax.ufl.edu GME Office 9th Floor, Tower I580 West 8th Street, T17Jacksonville, FL 32209Phone: (904) 244-9934Fax: (904) 244-9481 scott.silliman@jax.ufl.edu GME Program Assistant Shadina Williams(904) 244-9822Shadina.Williams@jax.ufl.edu Show More Clinical Research A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment duration study evaluating the efficacy and safety of Siponimod (BAF312) in patients with secondary progressive multiple sclerosis (20130508) A Multicenter, Global, Observational Study to Collect Information on Safety and to Document the Drug Utilization of Tecfidera™ (Dimethyl Fumarate) Education Medical Degree1988 · Albany Medical College, Albany, NY, USANeurology Residency1992 · Albert Einstein College of Medicine, Bronx, NY, USAVascular Neurology Fellowship1993 · Spaulding Rehabilitation Hospital New England Medical Center, Boston, MA, USA Show More News October 28, 2020 Measures have been taken to ensure graduate medical education remains strong amid COVID-19 July 30, 2020 Neurology residency program recognizes recent award winners February 28, 2019 'Fast Pass' to stroke recovery December 14, 2018 Comprehensive care for multiple sclerosis April 5, 2017 Patient thriving after surviving four strokes in 24 hours Media Coverage March 11, 2022 National Brain Injury Awareness Month: Bringing awareness to the causes and eliminating the stigma News4Jax (WJXT) September 1, 2021 Strokes & prolonged sitting News4Jax (WJXT) May 21, 2016 Loren McClendon comes home to pursue a career as a pediatric neurologist Florida Times-Union July 4, 2014 Jacksonville's UF Health, Mayo Clinic team up to educate EMS personnel on strokes News4Jax (WJXT) Multimedia May 21, 2015 Stroke warning signs